Plasmodium vivax dhfrMutations among Isolates from Malarious Areas of Iran
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منابع مشابه
Plasmodium vivax dhfr Mutations among Isolates from Malarious Areas of Iran
The use of sulfadoxine and pyrimethamine (SP) for treatment of vivax malaria is uncommon in most malarious areas, but Plasmodium vivax isolates are exposed to SP because of mixed infections with other Plasmodium species. As P. vivax is the most prevalent species of human malaria parasites in Iran, monitoring of resistance of the parasite against the drug is necessary. In the present study, 50 b...
متن کاملpartial sequence analysis of merozoite surface proteine-3α gene in plasmodium vivax isolates from malarious areas of iran
background: approximately 85-90% of malaria infections in iran are attributed to plasmodium vivax , while little is known about the genetic of the parasite and its strain types in this region. this study was designed and performed for describing genetic characteristics of plasmodium vivax population of iran based on the merozoite surface protein-3α gene sequence. methods: through a descriptive ...
متن کاملMOLECULAR SURVEILLANCE OF Plasmodium vivax AND Plasmodium falciparum DHFR MUTATIONS IN ISOLATES FROM SOUTHERN IRAN
In Iran, both Plasmodium vivax and P. falciparum malaria have been detected, but P. vivax is the predominant species. Point mutations in dihydrofolate reductase (dhfr) gene in both Plasmodia are the major mechanisms of pyrimethamine resistance. From April 2007 to June 2009, a total of 134 blood samples in two endemic areas of southern Iran were collected from patients infected with P. vivax and...
متن کاملAnalysis of Plasmodium vivax Apical Membrane Antigen-1 (PvAMA-1) Haplotypes among Iranian Isolates
Plasmodium vivax apical membrane antigen-1(PvAMA-1) is a surface protein with polymorphic sites. This study was aimed to analyze the polymorphic amino acid residues at PvAMA-1 in different infected age groups. 92 blood samples were collected from south and southeast of Iran. The DNA coding for the domain I (DI), DII, and partial DIII of this antigen was amplified by Nested-PCR, and sequenced. N...
متن کاملDetection of Plasmodium Vivax by Nested PCR in marious areas of western north of Iran
Introduction: Malaria is one of the most important parasitic diseases in tropical and sub-tropical areas of the world and kills a large number of People annually. Diagnosis of the disease is preformed by microscopic and molecular methods. This study has been designed for detecting of latent/sub-patent infection caused by plasmodium vivax in individuals with history of vivax malaria without an...
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ژورنال
عنوان ژورنال: The Korean Journal of Parasitology
سال: 2011
ISSN: 0023-4001
DOI: 10.3347/kjp.2011.49.2.125